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ACG

h.o.l.M.E.S.

Automated Clinical Guidelines

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Urea Cycle Disorder Agents
* Prices reflect U.S. average retail price
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Buphenyl (sodium phenylbutyrate)

Sodium phenylbutyrate is a salt of an aromatic fatty acid, 4-phenylbutyrate (4-PBA) or 4-phenylbutyric acid. The compound is used to treat urea cycle disorders, because its metabolites offer an alternative pathway to the urea cycle to allow excretion of excess nitrogen... Wikipedia

Manufacturer's Website: Not Available                                                                                         Average retail cost: *

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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Ravicti (glycerol phenylbutyrate)

Glycerol phenylbutyrate (USAN), trade name Ravicti, is a medication used in the treatment of certain inborn urea cycle disorders. The medication works by preventing the harmful buildup of ammonia in the body... Wikipedia

Manufacturer's Website: Ravicti                                                                                              Average retail cost: *

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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