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ACG
​
h.o.l.M.E.S.

Automated Clinical Guidelines

Zileuton (trade name Zyflo) is an orally active inhibitor of 5-lipoxygenase, and thus inhibits leukotrienes (LTB4, LTC4, LTD4, and LTE4) formation, used for the maintenance treatment of asthma...Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                                     Average retail cost: $2,237/60 tabs

Zyflo CR (zileuton)
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Leukotriene Modifiers

Zafirlukast is an orally administered leukotriene receptor antagonist (LTRA) used for the chronic treatment of asthma. While zafirlukast is generally well tolerated, headache and stomach upset often occur. Some rare side effects can occur, which can be life-threatening, such as liver failure...Wikipedia

 

Manufacturer's Website: Not Available                                                                                                                                        Average retail cost: $278/60 tabs

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Montelukast, sold under the brand name Singulair among others, is a medication used in the maintenance treatment of asthma. It is generally less preferred for this use than inhaled corticosteroids. It is not useful for acute asthma attacks. Other uses include allergic rhinitis and hives of long duration...Wikipedia

 

Manufacturer's Website: Singulair                                                                                                                                            Average retail cost: $312/30 tabs

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Accolate (zafirlukast)
Singulair (montelukast)
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* Prices reflect U.S. average retail price
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