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ACG

h.o.l.M.E.S.

Automated Clinical Guidelines

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Miscellaneous Respiratory Agents

Sodium chloride is used together with water as one of the primary solutions for intravenous therapy.

 

Manufacturer's Website: BD PosiFlush                                                                                                                                 Average retail cost: $70/carton

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Sodium Chloride is used to treat sodium loss due to dehydration and excessive sweating.

 

Manufacturer's Website: Not Available                                                                                                                                  Average retail cost: $125/60vial

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BD Posiflush SF (sodium chloride)
NebuSal (sodium chloride)

Dornase alfa (proprietary name Pulmozyme from Genentech) is a highly purified solution of recombinant human deoxyribonuclease I (rhDNase), an enzyme which selectively cleaves DNA. Dornase alfa hydrolyzes the DNA present in sputum/mucus of cystic fibrosis patients and reduces viscosity in the lungs, promoting improved clearance of secretions. This protein therapeutic agent is produced in Chinese hamster ovary cells ...Wikipedia

 

Manufacturer's Website: Pulmozyme                                                                                                                                                  Average retail cost: $4,695/carton

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ALPHA-1-PROTEINASE INHIBITOR (AL fa - 1 PRO tee nase in HIB i tor) is a drug that is used to replace an enzyme in patients with lung problems caused by low levels of alpha-1 antitrypsin (ATA). It is not a cure.

 

Manufacturer's Website: Aralast NP                                                                                                                                  Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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Pulmozyme (dornase alfa)
Aralast NP (alpha 1-proteinase inhibitor)

Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin) ...Wikipedia

 

Manufacturer's Website: Glassia                                                                                                                                  Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin) ...Wikipedia

 

Manufacturer's Website: Prolastin-C                                                                                                                                  Average retail cost: *

 

* This drug is only available at select specialty pharmacies, which usually means it may be expensive.

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Glassia (alpha 1-proteinase inhibitor)
Prolastin-C (alpha 1-proteinase inhibitor )

Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1 gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin) ...Wikipedia

 

Manufacturer's Website: Zemaira                                                                                                                                 Average retail cost: *

 

*This drug is administered by your healthcare practitioner, which usually means it may be expensive.

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Zemaira (alpha 1-proteinase inhibitor)
* Prices reflect U.S. average retail price
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